Endocrine Abstracts

Background: Patients with type 2 diabetes mellitus (T2DM) have elevated risk of coronary artery disease (CAD) development. In this population CAD often proceedsasymptomatically, especially if cardiac autonomic neuropathy (CAN) is present. Our aim was to assess relation between glycemia control and asymptomatic CAD inT2DM pts. Materials and methods: Participants were 160 T2DM patients without documented CAD divided into four groups (Gr.) according to HbA1c levels: Gr. 1 -HbA1c6...

Background: Sudomotor function is used to assessperipheral autonomic system. Electrochemical Skin Conductancemeasurement using electrochemical reaction betweenchloride ions in sweat and stainless steel plate electrodes is a simple, non-invasive and quick method. Several factors, including age, sex, BMI, glycemic status influence sweat function.Aim: Our aim was to determineprevalence of peripheral (DPN) and cardiac autonomic neuropathy (CAN) in hypertensi...

Background and aims: Mortality rate from cardiovascular disease (CV) including sudden death (SD) is pronounced in type 2 diabetic (T2DM) patients with cardiac autonomic neuropathy (CAN) and/or complex ventricular arrhythmias (CVA). Early repolarization (ER) is also considered to be a significant risk factor for SD. The aim of the study was to evaluation the relation between CAN, CVA and ER in T2DM patients.Materials and methods: Participants were 44 T2DM...

The aim of the present work was to assess the degree of glycemic control and complications rate through pregnancy and thirteen-years post-partum in women with microalbuminuria (T1DM).Materials and methodsIn total 191 patients with T1DM were enrolled in the study. Based on albuminuria levels in the 1st trimester women were separated into 2 groups (Gr.). Gr.1 – 116 women with normoalbuminuria, Gr.2 – 75 women wit...

Background: Hyperglycemia is believed to be the underlying cause for many of the adverse fetal, neonatal, and maternal outcomes in pregnancies complicated by type 1diabetes (T1DM). In particular, the rates of a large for gestational age (LGA) neonates and macrosomia remain high and suggest that hyperglycemia may not be the only driver of fetal overgrowth for women with T1DM.Aim: Our aim was to assess the association between gestational glycemic profiles ...

Background: Studies show relationship between serum uric acid (SUA) and such diseases as type 2 diabetes (T2DM), hypertension (HT) and atherosclerotic cardiovascular disease (ASCVD). There is relationship both in hyperuricemia (HU), and high–normal values of SUA. Significance of this association is unknown; there are controversial data concerning HU role in patients with T2DM/CVD. The aim of the study was to assess SUA in T2DM patients with ASCVD.<...

Our aim was to evaluate the efficacy of a structured outpatient education and treatment program (SOETP) in type 1 diabetes patients (T1DM) patients during preconception care (PC) and pregnancy, and its effect on pregnancy outcomes. Study Methods: In total 173 women with T1DM were supervised. Maternal age was 28±8 yrs and diabetes duration - 12±7yrs. SOETP combined group and individual training. Stage 1 - preconception care (group and individual training). Stage 2 - i...